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Dr. Óscar Asensio talks to us about the new challenges in the treatment of CF from the National Cystic Fibrosis Congress in Navarra, held in October.
Modulating treatments for the entire Cystic Fibrosis collective
In this informative capsule, Dr. Óscar Asensio, President of the Spanish Cystic Fibrosis Foundation and the Spanish Cystic Fibrosis Society, tells us that there are already new strategies that contemplate modulators for those mutations that were not covered.
In addition, steps are being taken towards a definitive cure for Cystic Fibrosis through genetics, although this is a difficult and lengthy process until the goal is achieved.
Is the application of phage therapy possible in the short term?
Dr. Asensio points out that those to whom the modulator has arrived late have physical sequelae in different organs. Therefore, one of the challenges is to attack those multidrug-resistant microorganisms for which there is no longer any effective antibiotic to stop the infection.
In his opinion, one of the most promising therapies is phage therapy, which has already been used on a compassionate basis in certain isolated cases with good results.
In this sense, he points out that the best option would be a clinical trial, with a large number of patients, in order to demonstrate the efficacy of this treatment.
More information on new treatments
Dr. Asensio summarizes both the challenges after modulators and treatments for other mutations in the video “New challenges in treatment: life after modulators” between minutes 13:20 and 20:15.
Another paper discusses “Minority mutations: upcoming treatments in development”.